DDTRP: Database of Drug Targets for Resistant Pathogens

Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We desc...

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Autores principales: Sundaramurthi, Jagadish Chandrabose, Ramanandan, Prabhakaran, Brindha, Sridharan, Subhasree, Chelladurai Ramarathnam, Prasad, Abhimanyu, Kumaraswami, Vasanthapuram, Hanna, Luke Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Database
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174044/
https://www.ncbi.nlm.nih.gov/pubmed/21938213
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author Sundaramurthi, Jagadish Chandrabose
Ramanandan, Prabhakaran
Brindha, Sridharan
Subhasree, Chelladurai Ramarathnam
Prasad, Abhimanyu
Kumaraswami, Vasanthapuram
Hanna, Luke Elizabeth
author_facet Sundaramurthi, Jagadish Chandrabose
Ramanandan, Prabhakaran
Brindha, Sridharan
Subhasree, Chelladurai Ramarathnam
Prasad, Abhimanyu
Kumaraswami, Vasanthapuram
Hanna, Luke Elizabeth
author_sort Sundaramurthi, Jagadish Chandrabose
collection PubMed
description Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called ‘Database of Drug Targets for Resistant Pathogens’ (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP.
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spelling pubmed-31740442011-09-21 DDTRP: Database of Drug Targets for Resistant Pathogens Sundaramurthi, Jagadish Chandrabose Ramanandan, Prabhakaran Brindha, Sridharan Subhasree, Chelladurai Ramarathnam Prasad, Abhimanyu Kumaraswami, Vasanthapuram Hanna, Luke Elizabeth Bioinformation Database Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called ‘Database of Drug Targets for Resistant Pathogens’ (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP. Biomedical Informatics 2011-09-06 /pmc/articles/PMC3174044/ /pubmed/21938213 Text en © 2011 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Database
Sundaramurthi, Jagadish Chandrabose
Ramanandan, Prabhakaran
Brindha, Sridharan
Subhasree, Chelladurai Ramarathnam
Prasad, Abhimanyu
Kumaraswami, Vasanthapuram
Hanna, Luke Elizabeth
DDTRP: Database of Drug Targets for Resistant Pathogens
title DDTRP: Database of Drug Targets for Resistant Pathogens
title_full DDTRP: Database of Drug Targets for Resistant Pathogens
title_fullStr DDTRP: Database of Drug Targets for Resistant Pathogens
title_full_unstemmed DDTRP: Database of Drug Targets for Resistant Pathogens
title_short DDTRP: Database of Drug Targets for Resistant Pathogens
title_sort ddtrp: database of drug targets for resistant pathogens
topic Database
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174044/
https://www.ncbi.nlm.nih.gov/pubmed/21938213
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