Protein network study of human AF4 reveals its central role in RNA Pol II-mediated transcription and in phosphorylation-dependent regulatory mechanisms

AF4 belongs to a family of proteins implicated in childhood lymphoblastic leukaemia, FRAXE (Fragile X E site) mental retardation and ataxia. AF4 is a transcriptional activator that is involved in transcriptional elongation. Although AF4 has been implicated in MLL (mixed-lineage leukaemia)-related le...

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Detalles Bibliográficos
Autores principales: Esposito, Gabriella, Cevenini, Armando, Cuomo, Alessandro, de Falco, Francesca, Sabbatino, Dario, Pane, Fabrizio, Ruoppolo, Margherita, Salvatore, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174057/
https://www.ncbi.nlm.nih.gov/pubmed/21574958
http://dx.doi.org/10.1042/BJ20101633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174057/
https://www.ncbi.nlm.nih.gov/pubmed/21574958
http://dx.doi.org/10.1042/BJ20101633

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