Cargando…
Familial tumoral calcinosis in two Chinese patients: a case series
INTRODUCTION: Tumoral calcinosis is a rare and benign condition characterized by massive subcutaneous soft tissue deposits of calcium phosphate predominantly around large joints. CASE PRESENTATION: Familial tumoral calcinosis was present in two members of a Han Chinese family, namely, the son and da...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174129/ https://www.ncbi.nlm.nih.gov/pubmed/21854601 http://dx.doi.org/10.1186/1752-1947-5-394 |
_version_ | 1782212031733039104 |
---|---|
author | Zhang, Che Gu, Jiaowei Cheng, Xiaoli Xiong, Kui |
author_facet | Zhang, Che Gu, Jiaowei Cheng, Xiaoli Xiong, Kui |
author_sort | Zhang, Che |
collection | PubMed |
description | INTRODUCTION: Tumoral calcinosis is a rare and benign condition characterized by massive subcutaneous soft tissue deposits of calcium phosphate predominantly around large joints. CASE PRESENTATION: Familial tumoral calcinosis was present in two members of a Han Chinese family, namely, the son and daughter. The 14-year-old son had the first operation on his right sole of the foot at the age of six, and then experienced subsequent surgeries at a lesion in his right sole of the foot and left hip, respectively. The 16-year-old daughter underwent her first operation at the age of six in her left gluteal region, and subsequent surgeries were performed due to recurrence at the same lesion. Pathologic diagnoses of surgical specimens in both of the patients were reported as tumoral calcinosis. The laboratory results showed hyperphosphatemia with normal levels of serum calcium and alkaline phosphatase. Only surgical treatment was performed in both patients with satisfactory prognosis. CONCLUSION: This is the first report of Chinese familial tumoral calcinosis. The etiopathogenisis and treatment are discussed. |
format | Online Article Text |
id | pubmed-3174129 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-31741292011-09-16 Familial tumoral calcinosis in two Chinese patients: a case series Zhang, Che Gu, Jiaowei Cheng, Xiaoli Xiong, Kui J Med Case Reports Case Report INTRODUCTION: Tumoral calcinosis is a rare and benign condition characterized by massive subcutaneous soft tissue deposits of calcium phosphate predominantly around large joints. CASE PRESENTATION: Familial tumoral calcinosis was present in two members of a Han Chinese family, namely, the son and daughter. The 14-year-old son had the first operation on his right sole of the foot at the age of six, and then experienced subsequent surgeries at a lesion in his right sole of the foot and left hip, respectively. The 16-year-old daughter underwent her first operation at the age of six in her left gluteal region, and subsequent surgeries were performed due to recurrence at the same lesion. Pathologic diagnoses of surgical specimens in both of the patients were reported as tumoral calcinosis. The laboratory results showed hyperphosphatemia with normal levels of serum calcium and alkaline phosphatase. Only surgical treatment was performed in both patients with satisfactory prognosis. CONCLUSION: This is the first report of Chinese familial tumoral calcinosis. The etiopathogenisis and treatment are discussed. BioMed Central 2011-08-19 /pmc/articles/PMC3174129/ /pubmed/21854601 http://dx.doi.org/10.1186/1752-1947-5-394 Text en Copyright ©2011 Zhang et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Zhang, Che Gu, Jiaowei Cheng, Xiaoli Xiong, Kui Familial tumoral calcinosis in two Chinese patients: a case series |
title | Familial tumoral calcinosis in two Chinese patients: a case series |
title_full | Familial tumoral calcinosis in two Chinese patients: a case series |
title_fullStr | Familial tumoral calcinosis in two Chinese patients: a case series |
title_full_unstemmed | Familial tumoral calcinosis in two Chinese patients: a case series |
title_short | Familial tumoral calcinosis in two Chinese patients: a case series |
title_sort | familial tumoral calcinosis in two chinese patients: a case series |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174129/ https://www.ncbi.nlm.nih.gov/pubmed/21854601 http://dx.doi.org/10.1186/1752-1947-5-394 |
work_keys_str_mv | AT zhangche familialtumoralcalcinosisintwochinesepatientsacaseseries AT gujiaowei familialtumoralcalcinosisintwochinesepatientsacaseseries AT chengxiaoli familialtumoralcalcinosisintwochinesepatientsacaseseries AT xiongkui familialtumoralcalcinosisintwochinesepatientsacaseseries |