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Involvement of the Glycogen Synthase Kinase-3 Signaling Pathway in TBI Pathology and Neurocognitive Outcome

BACKGROUND: Traumatic brain injury (TBI) sets in motion cascades of biochemical changes that result in delayed cell death and altered neuronal architecture. Studies have demonstrated that inhibition of glycogen synthase kinase-3 (GSK-3) effectively reduces apoptosis following a number of stimuli. Th...

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Detalles Bibliográficos
Autores principales: Dash, Pramod K., Johnson, Daniel, Clark, Jordan, Orsi, Sara A., Zhang, Min, Zhao, Jing, Grill, Raymond J., Moore, Anthony N., Pati, Shibani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174188/
https://www.ncbi.nlm.nih.gov/pubmed/21935433
http://dx.doi.org/10.1371/journal.pone.0024648