Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

MicroRNAs regulate networks of genes to orchestrate cellular functions. MiR-125b, the vertebrate homologue of the Caenorhabditis elegans microRNA lin-4, has been implicated in the regulation of neural and hematopoietic stem cell homeostasis, analogous to how lin-4 regulates stem cells in C. elegans....

Descripción completa

Detalles Bibliográficos
Autores principales: Le, Minh T. N., Shyh-Chang, Ng, Khaw, Swea Ling, Chin, Lingzi, Teh, Cathleen, Tay, Junliang, O'Day, Elizabeth, Korzh, Vladimir, Yang, Henry, Lal, Ashish, Lieberman, Judy, Lodish, Harvey F., Lim, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174204/
https://www.ncbi.nlm.nih.gov/pubmed/21935352
http://dx.doi.org/10.1371/journal.pgen.1002242

Ejemplares similares

Ejemplares similares