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Identification of a Negative Allosteric Site on Human α4β2 and α3β4 Neuronal Nicotinic Acetylcholine Receptors

Acetylcholine-based neurotransmission is regulated by cationic, ligand-gated ion channels called nicotinic acetylcholine receptors (nAChRs). These receptors have been linked to numerous neurological diseases and disorders such as Alzheimer's disease, Parkinson's disease, and nicotine addic...

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Detalles Bibliográficos
Autores principales:	Pavlovicz, Ryan E., Henderson, Brandon J., Bonnell, Andrew B., Boyd, R. Thomas, McKay, Dennis B., Li, Chenglong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174232/ https://www.ncbi.nlm.nih.gov/pubmed/21949802 http://dx.doi.org/10.1371/journal.pone.0024949

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