A Viral Ubiquitin Ligase Has Substrate Preferential SUMO Targeted Ubiquitin Ligase Activity that Counteracts Intrinsic Antiviral Defence

Intrinsic antiviral resistance represents the first line of intracellular defence against virus infection. During herpes simplex virus type-1 (HSV-1) infection this response can lead to the repression of viral gene expression but is counteracted by the viral ubiquitin ligase ICP0. Here we address th...

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Detalles Bibliográficos
Autores principales: Boutell, Chris, Cuchet-Lourenço, Delphine, Vanni, Emilia, Orr, Anne, Glass, Mandy, McFarlane, Steven, Everett, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174244/
https://www.ncbi.nlm.nih.gov/pubmed/21949651
http://dx.doi.org/10.1371/journal.ppat.1002245

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