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HSV Infection Induces Production of ROS, which Potentiate Signaling from Pattern Recognition Receptors: Role for S-glutathionylation of TRAF3 and 6
The innate immune response constitutes the first line of defense against infections. Pattern recognition receptors recognize pathogen structures and trigger intracellular signaling pathways leading to cytokine and chemokine expression. Reactive oxygen species (ROS) are emerging as an important regul...
Autores principales: | Gonzalez-Dosal, Regina, Horan, Kristy A., Rahbek, Stine H., Ichijo, Hidenori, Chen, Zhijian J., Mieyal, John J., Hartmann, Rune, Paludan, Søren R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174249/ https://www.ncbi.nlm.nih.gov/pubmed/21949653 http://dx.doi.org/10.1371/journal.ppat.1002250 |
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