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MMP9 deficiency does not decrease blood–brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis
Expression of matrix metalloproteinases (MMPs), especially MMP9 correlates with blood–brain barrier (BBB) disruption during many neuroinflammatory diseases. During neurotropic coronavirus virus (JHMV) induced encephalomyelitis, MMP9 activity is restricted to neutrophils. Furthermore, myeloid cell de...
Autores principales: | Savarin, Carine, Stohlman, Stephen A., Rietsch, Anna M., Butchi, Niranjan, Ransohoff, Richard M., Bergmann, Cornelia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174277/ https://www.ncbi.nlm.nih.gov/pubmed/21800363 http://dx.doi.org/10.1002/glia.21222 |
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