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Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation
TGF-β1 has been long considered as a key mediator in renal fibrosis and induces renal scarring largely by activating its downstream Smad signaling pathway. Interestingly, while mice overexpressing active TGF-β1 develop progressive renal injury, latent TGF-β1 plays a protective role in renal fibrosis...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Ivyspring International Publisher
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174390/ https://www.ncbi.nlm.nih.gov/pubmed/21927575 |