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Preserved arterial vasodilatation via endothelial protease-activated receptor-2 in obese type 2 diabetic mice
BACKGROUND AND PURPOSE: In non-obese diabetic animals, protease-activated receptor-2 (PAR2) agonists are more effective vasodilators, which is attributed to increased COX-2 and endothelial NOS (eNOS) activities. Under conditions of diabetes and obesity, the effectiveness of PAR2 agonists is unknown....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174416/ https://www.ncbi.nlm.nih.gov/pubmed/21426317 http://dx.doi.org/10.1111/j.1476-5381.2011.01356.x |