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Ceruloplasmin Deficiency Reduces Levels of Iron and BDNF in the Cortex and Striatum of Young Mice and Increases Their Vulnerability to Stroke
Ceruloplasmin (Cp) is an essential ferroxidase that plays important roles in cellular iron trafficking. Previous findings suggest that the proper regulation and subcellular localization of iron are very important in brain cell function and viability. Brain iron dyshomeostasis is observed during norm...
Autores principales: | Texel, Sarah J., Zhang, Jian, Camandola, Simonetta, Unger, Erica L., Taub, Dennis D., Koehler, Raymond C., Harris, Z. Leah, Mattson, Mark P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174999/ https://www.ncbi.nlm.nih.gov/pubmed/21949858 http://dx.doi.org/10.1371/journal.pone.0025077 |
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