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TRANSGENE-MEDIATED EXPRESSION OF TUMOR NECROSIS FACTOR SOLUBLE RECEPTOR ATTENUATES MORPHINE TOLERANCE IN RATS

Opiate/narcotic analgesics are the most effective treatments for chronic severe pain, but their clinical utility is often hampered by the development of analgesic tolerance. Recent evidence suggests chronic morphine may activate glial cells to release proinflammatory cytokines. In this study, we use...

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Detalles Bibliográficos
Autores principales:	Sun, Jingxia, Liu, Shue, Mata, Marina, Fink, David J., Hao, Shuanglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175012/ https://www.ncbi.nlm.nih.gov/pubmed/21614028 http://dx.doi.org/10.1038/gt.2011.76

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