The effects of stem length and core placement on shRNA activity

BACKGROUND: Expressed short hairpin RNAs (shRNA) used in mammalian RNA interference (RNAi) are often designed around a specific short interfering RNA (siRNA) core. Whilst there are algorithms to aid siRNA design, hairpin-specific characteristics such as stem-length and siRNA core placement within th...

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Detalles Bibliográficos
Autores principales: Mcintyre, Glen J, Yu, Yi-Hsin, Lomas, Mehnaaz, Fanning, Gregory C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175162/
https://www.ncbi.nlm.nih.gov/pubmed/21819628
http://dx.doi.org/10.1186/1471-2199-12-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175162/
https://www.ncbi.nlm.nih.gov/pubmed/21819628
http://dx.doi.org/10.1186/1471-2199-12-34

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