Kinetic Targeting of pegylated liposomal Doxorubicin: a new Approach to Reduce Toxicity during Chemotherapy (CARL-trial)

BACKGROUND: The therapeutic success of chemotherapeutic agents is often limited by severe adverse effects. To reduce toxicity of these drugs, nanoscale particle-based drug delivery systems (DDS) are used. DDS accumulate to some extent in tumor tissues, but only a very small portion of a given dose r...

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Detalles Bibliográficos
Autores principales: Eckes, Jürgen, Schmah, Oliver, Siebers, Jan W, Groh, Ursula, Zschiedrich, Stefan, Rautenberg, Beate, Hasenburg, Annette, Jansen, Martin, Hug, Martin J, Winkler, Karl, Pütz, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175222/
https://www.ncbi.nlm.nih.gov/pubmed/21816044
http://dx.doi.org/10.1186/1471-2407-11-337

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