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Large-Scale Bi-Level Strain Design Approaches and Mixed-Integer Programming Solution Techniques
The use of computational models in metabolic engineering has been increasing as more genome-scale metabolic models and computational approaches become available. Various computational approaches have been developed to predict how genetic perturbations affect metabolic behavior at a systems level, an...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175644/ https://www.ncbi.nlm.nih.gov/pubmed/21949695 http://dx.doi.org/10.1371/journal.pone.0024162 |