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Gene- or region-based association study via kernel principal component analysis

BACKGROUND: In genetic association study, especially in GWAS, gene- or region-based methods have been more popular to detect the association between multiple SNPs and diseases (or traits). Kernel principal component analysis combined with logistic regression test (KPCA-LRT) has been successfully use...

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Detalles Bibliográficos
Autores principales:	Gao, Qingsong, He, Yungang, Yuan, Zhongshang, Zhao, Jinghua, Zhang, Bingbing, Xue, Fuzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176196/ https://www.ncbi.nlm.nih.gov/pubmed/21871061 http://dx.doi.org/10.1186/1471-2156-12-75

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