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LIP expression is regulated by IGF-1R signaling and participates in suppression of anoikis

BACKGROUND: The transcription factor, CCAAT enhancer binding protein-β (C/EBPβ), is expressed as several distinct protein isoforms (LAP1, LAP2 and LIP) that have opposing actions in cellular proliferation and differentiation. Increases in the ratio of LIP/LAP are associated with aggressive, metastat...

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Detalles Bibliográficos
Autores principales: Li, Huili, Baldwin, Brenda R, Zahnow, Cynthia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176234/
https://www.ncbi.nlm.nih.gov/pubmed/21854628
http://dx.doi.org/10.1186/1476-4598-10-100