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Perspective on sequence evolution of microsatellite locus (CCG)(n )in Rv0050 gene from Mycobacterium tuberculosis
BACKGROUND: The mycobacterial genome is inclined to polymerase slippage and a high mutation rate in microsatellite regions due to high GC content and absence of a mismatch repair system. However, the exact molecular mechanisms underlying microsatellite variation have not been fully elucidated. Here,...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176237/ https://www.ncbi.nlm.nih.gov/pubmed/21878130 http://dx.doi.org/10.1186/1471-2148-11-247 |