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Perspective on sequence evolution of microsatellite locus (CCG)(n )in Rv0050 gene from Mycobacterium tuberculosis

BACKGROUND: The mycobacterial genome is inclined to polymerase slippage and a high mutation rate in microsatellite regions due to high GC content and absence of a mismatch repair system. However, the exact molecular mechanisms underlying microsatellite variation have not been fully elucidated. Here,...

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Detalles Bibliográficos
Autores principales: Qin, Lianhua, Wang, Jie, Zheng, Ruijuan, Lu, Junmei, Yang, Hua, Liu, Zhonghua, Cui, Zhenling, Jin, Ruiliang, Feng, Yonghong, Hu, Zhongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176237/
https://www.ncbi.nlm.nih.gov/pubmed/21878130
http://dx.doi.org/10.1186/1471-2148-11-247