Rigorous assessment and integration of the sequence and structure based features to predict hot spots

BACKGROUND: Systematic mutagenesis studies have shown that only a few interface residues termed hot spots contribute significantly to the binding free energy of protein-protein interactions. Therefore, hot spots prediction becomes increasingly important for well understanding the essence of proteins...

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Detalles Bibliográficos
Autores principales: Chen, Ruoying, Chen, Wenjing, Yang, Sixiao, Wu, Di, Wang, Yong, Tian, Yingjie, Shi, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176265/
https://www.ncbi.nlm.nih.gov/pubmed/21798070
http://dx.doi.org/10.1186/1471-2105-12-311

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