The Regulation of Skeletal Muscle Protein Turnover during the Progression of Cancer Cachexia in the Apc(Min/+) Mouse

Muscle wasting that occurs with cancer cachexia is caused by an imbalance in the rates of muscle protein synthesis and degradation. The Apc(Min/+) mouse is a model of colorectal cancer that develops cachexia that is dependent on circulating IL-6. However, the IL-6 regulation of muscle protein turnov...

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Detalles Bibliográficos
Autores principales: White, James P., Baynes, John W., Welle, Stephen L., Kostek, Matthew C., Matesic, Lydia E., Sato, Shuichi, Carson, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176277/
https://www.ncbi.nlm.nih.gov/pubmed/21949739
http://dx.doi.org/10.1371/journal.pone.0024650

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