HCV Causes Chronic Endoplasmic Reticulum Stress Leading to Adaptation and Interference with the Unfolded Protein Response

BACKGROUND: The endoplasmic reticulum (ER) is the cellular site for protein folding. ER stress occurs when protein folding capacity is exceeded. This stress induces a cyto-protective signaling cascades termed the unfolded protein response (UPR) aimed at restoring homeostasis. While acute ER stress i...

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Detalles Bibliográficos
Autores principales: Merquiol, Emmanuelle, Uzi, Dotan, Mueller, Tobias, Goldenberg, Daniel, Nahmias, Yaakov, Xavier, Ramnik J., Tirosh, Boaz, Shibolet, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176279/
https://www.ncbi.nlm.nih.gov/pubmed/21949742
http://dx.doi.org/10.1371/journal.pone.0024660

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