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Administration of Simvastatin after Kainic Acid-Induced Status Epilepticus Restrains Chronic Temporal Lobe Epilepsy

In this study, we examined the effect of chronic administration of simvastatin immediately after status epilepticus (SE) on rat brain with temporal lobe epilepsy (TLE). First, we evaluated cytokines expression at 3 days post KA-lesion in hippocampus and found that simvastatin-treatment suppressed le...

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Detalles Bibliográficos
Autores principales: Xie, Chuncheng, Sun, Jiahang, Qiao, Weidong, Lu, Dunyue, Wei, Lanlan, Na, Meng, Song, Yuanyuan, Hou, Xiaohua, Lin, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176286/
https://www.ncbi.nlm.nih.gov/pubmed/21949812
http://dx.doi.org/10.1371/journal.pone.0024966