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Evidence Implicating the Ras Pathway in Multiple CD28 Costimulatory Functions in CD4(+) T Cells
CD28 costimulation is a critical event in the full activation of CD4(+) T cells that augments cytokine gene transcription, promotes cytokine mRNA stability, prevents induction of anergy, increases cellular metabolism, and increases cell survival. However, despite extensive biochemical analysis of th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176298/ https://www.ncbi.nlm.nih.gov/pubmed/21949793 http://dx.doi.org/10.1371/journal.pone.0024931 |