Screening for EGFR and KRAS Mutations in Endobronchial Ultrasound Derived Transbronchial Needle Aspirates in Non-Small Cell Lung Cancer Using COLD-PCR

EGFR mutations correlate with improved clinical outcome whereas KRAS mutations are associated with lack of response to tyrosine kinase inhibitors in patients with non-small cell lung cancer (NSCLC). Endobronchial ultrasound (EBUS)-transbronchial needle aspiration (TBNA) is being increasingly used in...

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Detalles Bibliográficos
Autores principales: Santis, George, Angell, Roger, Nickless, Guillermina, Quinn, Alison, Herbert, Amanda, Cane, Paul, Spicer, James, Breen, Ronan, McLean, Emma, Tobal, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176319/
https://www.ncbi.nlm.nih.gov/pubmed/21949883
http://dx.doi.org/10.1371/journal.pone.0025191

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