Cargando…
Comparison of distribution and activity of nanoparticles with short interfering DNA (Dbait) in various living systems
Introducing small DNA molecules (Dbait) impairs the repair of damaged chromosomes and provides a new method for enhancing the efficiency of radiotherapy in radio-resistant tumors. The radiosensitizing activity is dependent upon the efficient delivery of Dbait molecules into the tumor cells. Differen...
Autores principales: | Berthault, N, Maury, B, Agrario, C, Herbette, A, Sun, J-S, Peyrieras, N, Dutreix, M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176463/ https://www.ncbi.nlm.nih.gov/pubmed/21799529 http://dx.doi.org/10.1038/cgt.2011.39 |
Ejemplares similares
-
Pharmacokinetics and Toxicity in Rats and Monkeys of coDbait: A Therapeutic Double-stranded DNA Oligonucleotide Conjugated to Cholesterol
por: Schlegel, Anne, et al.
Publicado: (2012) -
Therapeutic approach of human peritoneal carcinomatosis with Dbait in combination with capnoperitoneum: proof of concept
por: Solass, Wiebke, et al.
Publicado: (2011) -
Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Glioblastoma
por: Coquery, Nicolas, et al.
Publicado: (2012) -
Targeting DNA repair by coDbait enhances melanoma targeted radionuclide therapy
por: Viallard, Claire, et al.
Publicado: (2016) -
Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models
por: Biau, Julian, et al.
Publicado: (2019)