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Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis
BACKGROUND: Osteoarthritis (OA) is a debilitating, progressive joint disease. METHODS: Similar to the disease progression in humans, sequential events of early cartilage degradation, subchondral osteopenia followed by sclerosis, and late osteophyte formation were demonstrated in the anterior cruciat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176489/ https://www.ncbi.nlm.nih.gov/pubmed/21864409 http://dx.doi.org/10.1186/1471-2474-12-197 |