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Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a debilitating, progressive joint disease. METHODS: Similar to the disease progression in humans, sequential events of early cartilage degradation, subchondral osteopenia followed by sclerosis, and late osteophyte formation were demonstrated in the anterior cruciat...

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Detalles Bibliográficos
Autores principales:	Pickarski, Maureen, Hayami, Tadashi, Zhuo, Ya, Duong, Le T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176489/ https://www.ncbi.nlm.nih.gov/pubmed/21864409 http://dx.doi.org/10.1186/1471-2474-12-197

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