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Assessing the Effects of Symmetry on Motif Discovery and Modeling

BACKGROUND: Identifying the DNA binding sites for transcription factors is a key task in modeling the gene regulatory network of a cell. Predicting DNA binding sites computationally suffers from high false positives and false negatives due to various contributing factors, including the inaccurate mo...

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Detalles Bibliográficos
Autores principales: Motlhabi, Lala M., Stormo, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176789/
https://www.ncbi.nlm.nih.gov/pubmed/21949783
http://dx.doi.org/10.1371/journal.pone.0024908