A Single Amino Acid Mutation in SNAP-25 Induces Anxiety-Related Behavior in Mouse

Synaptosomal-associated protein of 25 kDa (SNAP-25) is a presynaptic protein essential for neurotransmitter release. Previously, we demonstrate that protein kinase C (PKC) phosphorylates Ser(187) of SNAP-25, and enhances neurotransmitter release by recruiting secretory vesicles near to the plasma me...

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Detalles Bibliográficos
Autores principales: Kataoka, Masakazu, Yamamori, Saori, Suzuki, Eiji, Watanabe, Shigeru, Sato, Taku, Miyaoka, Hitoshi, Azuma, Sadahiro, Ikegami, Shiro, Kuwahara, Reiko, Suzuki-Migishima, Rika, Nakahara, Yohko, Nihonmatsu, Itsuko, Inokuchi, Kaoru, Katoh-Fukui, Yuko, Yokoyama, Minesuke, Takahashi, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176821/
https://www.ncbi.nlm.nih.gov/pubmed/21949876
http://dx.doi.org/10.1371/journal.pone.0025158

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