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The orally active melanocortin-4 receptor antagonist BL-6020/979: a promising candidate for the treatment of cancer cachexia

BACKGROUND: Under physiological conditions, the melanocortin system is a crucial part of the complex network regulating food intake and energy expenditure. In pathological states, like cachexia, these two parameters are deregulated, i.e., food intake is decreased and energy expenditure is increased—...

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Detalles Bibliográficos
Autores principales: Dallmann, R., Weyermann, P., Anklin, C., Boroff, M., Bray-French, K., Cardel, B., Courdier-Fruh, I., Deppe, H., Dubach-Powell, J., Erb, M., Haefeli, R. H., Henneböhle, M., Herzner, H., Hufschmid, M., Marks, D. L., Nordhoff, S., Papp, M., Rummey, C., Santos, G., Schärer, F., Siendt, H., Soeberdt, M., Sumanovski, L. T., Terinek, M., Mondadori, C., Güven, N., Feurer, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177041/
https://www.ncbi.nlm.nih.gov/pubmed/21966642
http://dx.doi.org/10.1007/s13539-011-0039-1