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ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

Transcriptional control is dependent on a vast network of epigenetic modifications. One epigenetic mark of particular interest is tri-methylation of lysine 27 on histone H3 (H3K27me3), which is catalysed and maintained by Polycomb Repressive Complex 2 (PRC2). Although this histone mark is studied wi...

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Detalles Bibliográficos
Autores principales:	Young, Matthew D., Willson, Tracy A., Wakefield, Matthew J., Trounson, Evelyn, Hilton, Douglas J., Blewitt, Marnie E., Oshlack, Alicia, Majewski, Ian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177187/ https://www.ncbi.nlm.nih.gov/pubmed/21652639 http://dx.doi.org/10.1093/nar/gkr416

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