Cargando…
DNA slip-outs cause RNA polymerase II arrest in vitro: potential implications for genetic instability
The abnormal number of repeats found in triplet repeat diseases arises from ‘repeat instability’, in which the repetitive section of DNA is subject to a change in copy number. Recent studies implicate transcription in a mechanism for repeat instability proposed to involve RNA polymerase II (RNAPII)...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177194/ https://www.ncbi.nlm.nih.gov/pubmed/21666257 http://dx.doi.org/10.1093/nar/gkr429 |