Enhancers in embryonic stem cells are enriched for transposable elements and genetic variations associated with cancers

Using an enhancer-associated epigenetic signature, we made genome-wide predictions of transcriptional enhancers in human B and T lymphocytes and embryonic stem cells (ES cells). We validated and characterized the predicted enhancers using four types of information, including overlap with other genom...

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Detalles Bibliográficos
Autores principales: Teng, Li, Firpi, Hiram A., Tan, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177211/
https://www.ncbi.nlm.nih.gov/pubmed/21685454
http://dx.doi.org/10.1093/nar/gkr476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177211/
https://www.ncbi.nlm.nih.gov/pubmed/21685454
http://dx.doi.org/10.1093/nar/gkr476

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