Cargando…
Enhancers in embryonic stem cells are enriched for transposable elements and genetic variations associated with cancers
Using an enhancer-associated epigenetic signature, we made genome-wide predictions of transcriptional enhancers in human B and T lymphocytes and embryonic stem cells (ES cells). We validated and characterized the predicted enhancers using four types of information, including overlap with other genom...
Autores principales: | Teng, Li, Firpi, Hiram A., Tan, Kai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177211/ https://www.ncbi.nlm.nih.gov/pubmed/21685454 http://dx.doi.org/10.1093/nar/gkr476 |
Ejemplares similares
-
TEMP: a computational method for analyzing transposable element polymorphism in populations
por: Zhuang, Jiali, et al.
Publicado: (2014) -
Functional evaluation of transposable elements as enhancers in mouse embryonic and trophoblast stem cells
por: Todd, Christopher D, et al.
Publicado: (2019) -
Transposable elements drive rapid phenotypic variation in Capsella rubella
por: Niu, Xiao-Min, et al.
Publicado: (2019) -
Human population-specific gene expression and transcriptional network modification with polymorphic transposable elements
por: Wang, Lu, et al.
Publicado: (2017) -
Transposable elements activation triggers necroptosis in mouse embryonic stem cells
por: Jin, Lingmei, et al.
Publicado: (2023)