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Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1

Translation of many cellular and viral mRNAs is directed by internal ribosomal entry sites (IRESs). Several proteins that enhance IRES activity through interactions with IRES elements have been discovered. However, the molecular basis for the IRES-activating function of the IRES-binding proteins rem...

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Detalles Bibliográficos
Autores principales: Park, Sung Mi, Paek, Ki Young, Hong, Ka Young, Jang, Christopher J., Cho, Sungchan, Park, Ji Hoon, Kim, Jong Heon, Jan, Eric, Jang, Sung Key
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177222/
https://www.ncbi.nlm.nih.gov/pubmed/21715376
http://dx.doi.org/10.1093/nar/gkr509