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Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1
Translation of many cellular and viral mRNAs is directed by internal ribosomal entry sites (IRESs). Several proteins that enhance IRES activity through interactions with IRES elements have been discovered. However, the molecular basis for the IRES-activating function of the IRES-binding proteins rem...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177222/ https://www.ncbi.nlm.nih.gov/pubmed/21715376 http://dx.doi.org/10.1093/nar/gkr509 |