Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland

BACKGROUND: Patients with primary Sjögren's syndrome (pSS) produce functional IgG against cholinoreceptor of exocrine glands modifying their activity. The aim of the present work was to demonstrate pSS IgG antibodies (pSS IgG) interacting with M(3) muscarinic acetylcholine receptors (mAChR) of...

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Detalles Bibliográficos
Autores principales: Passafaro, Daniela, Sterin-Borda, Leonor, Reina, Silvia, Borda, Enri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177389/
https://www.ncbi.nlm.nih.gov/pubmed/22013477

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