The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death

Human endometrial stromal cells (HESCs) exposed to reactive oxygen species (ROS) mount a hypersumoylation response in a c-Jun N-terminal kinase (JNK)-dependent manner. The mechanism that couples JNK signaling to the small ubiquitin-related modifier (SUMO) pathway and its functional consequences are...

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Detalles Bibliográficos
Autores principales: Leitao, Beatriz B., Jones, Marius C., Brosens, Jan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2011
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177572/
https://www.ncbi.nlm.nih.gov/pubmed/21676946
http://dx.doi.org/10.1096/fj.11-186346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177572/
https://www.ncbi.nlm.nih.gov/pubmed/21676946
http://dx.doi.org/10.1096/fj.11-186346

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