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The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death
Human endometrial stromal cells (HESCs) exposed to reactive oxygen species (ROS) mount a hypersumoylation response in a c-Jun N-terminal kinase (JNK)-dependent manner. The mechanism that couples JNK signaling to the small ubiquitin-related modifier (SUMO) pathway and its functional consequences are...
Autores principales: | Leitao, Beatriz B., Jones, Marius C., Brosens, Jan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177572/ https://www.ncbi.nlm.nih.gov/pubmed/21676946 http://dx.doi.org/10.1096/fj.11-186346 |
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