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RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

Malignant glioma represents the most common primary adult brain tumor in Western industrialized countries. Despite aggressive treatment modalities, the median survival duration for patients with glioblastoma multiforme (GBM), the highest grade malignant glioma, has not improved significantly over pa...

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Detalles Bibliográficos
Autores principales:	Hendruschk, Sandy, Wiedemuth, Ralf, Aigner, Achim, Töpfer, Katrin, Cartellieri, Marc, Martin, Daniel, Kirsch, Matthias, Ikonomidou, Chrysanthy, Schackert, Gabriele, Temme, Achim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177660/ https://www.ncbi.nlm.nih.gov/pubmed/21788344 http://dx.doi.org/10.1093/neuonc/nor098

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