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Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the U.S.
OBJECTIVE: Metabolic risk and metabolic syndrome (MetSyn) prevalence were compared in Africans who immigrated to the U.S. and African Americans. If MetSyn were an effective predictor of cardiometabolic risk, then the group with a worse metabolic risk profile would have a higher rate of MetSyn. RESEA...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177749/ https://www.ncbi.nlm.nih.gov/pubmed/21873563 http://dx.doi.org/10.2337/dc11-1055 |
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author | Ukegbu, Ugochi J. Castillo, Darleen C. Knight, Michael G. Ricks, Madia Miller, Bernard V. Onumah, Barbara M. Sumner, Anne E. |
author_facet | Ukegbu, Ugochi J. Castillo, Darleen C. Knight, Michael G. Ricks, Madia Miller, Bernard V. Onumah, Barbara M. Sumner, Anne E. |
author_sort | Ukegbu, Ugochi J. |
collection | PubMed |
description | OBJECTIVE: Metabolic risk and metabolic syndrome (MetSyn) prevalence were compared in Africans who immigrated to the U.S. and African Americans. If MetSyn were an effective predictor of cardiometabolic risk, then the group with a worse metabolic risk profile would have a higher rate of MetSyn. RESEARCH DESIGN AND METHODS: Cross-sectional analyses were performed on 95 men (39 Africans, 56 African Americans, age 38 ± 6 years [mean ± SD]). Glucose tolerance was determined by oral glucose tolerance test, visceral adipose tissue (VAT) was determined by computerized tomography, and MetSyn was determined by the presence of three of five factors: central obesity, hypertriglyceridemia, low levels of HDL cholesterol, hypertension, and fasting hyperglycemia. RESULTS: MetSyn prevalence was similar in Africans and African Americans (10 vs. 13%, P = 0.74), but hypertension, glycemia (fasting and 2-h glucose), and VAT were higher in Africans. CONCLUSIONS: African immigrants have a worse metabolic profile than African Americans but a similar prevalence of MetSyn. Therefore, MetSyn may underpredict metabolic risk in Africans. |
format | Online Article Text |
id | pubmed-3177749 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | American Diabetes Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-31777492012-10-01 Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the U.S. Ukegbu, Ugochi J. Castillo, Darleen C. Knight, Michael G. Ricks, Madia Miller, Bernard V. Onumah, Barbara M. Sumner, Anne E. Diabetes Care Original Research OBJECTIVE: Metabolic risk and metabolic syndrome (MetSyn) prevalence were compared in Africans who immigrated to the U.S. and African Americans. If MetSyn were an effective predictor of cardiometabolic risk, then the group with a worse metabolic risk profile would have a higher rate of MetSyn. RESEARCH DESIGN AND METHODS: Cross-sectional analyses were performed on 95 men (39 Africans, 56 African Americans, age 38 ± 6 years [mean ± SD]). Glucose tolerance was determined by oral glucose tolerance test, visceral adipose tissue (VAT) was determined by computerized tomography, and MetSyn was determined by the presence of three of five factors: central obesity, hypertriglyceridemia, low levels of HDL cholesterol, hypertension, and fasting hyperglycemia. RESULTS: MetSyn prevalence was similar in Africans and African Americans (10 vs. 13%, P = 0.74), but hypertension, glycemia (fasting and 2-h glucose), and VAT were higher in Africans. CONCLUSIONS: African immigrants have a worse metabolic profile than African Americans but a similar prevalence of MetSyn. Therefore, MetSyn may underpredict metabolic risk in Africans. American Diabetes Association 2011-10 2011-09-15 /pmc/articles/PMC3177749/ /pubmed/21873563 http://dx.doi.org/10.2337/dc11-1055 Text en © 2011 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details. |
spellingShingle | Original Research Ukegbu, Ugochi J. Castillo, Darleen C. Knight, Michael G. Ricks, Madia Miller, Bernard V. Onumah, Barbara M. Sumner, Anne E. Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the U.S. |
title | Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the U.S. |
title_full | Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the U.S. |
title_fullStr | Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the U.S. |
title_full_unstemmed | Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the U.S. |
title_short | Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the U.S. |
title_sort | metabolic syndrome does not detect metabolic risk in african men living in the u.s. |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177749/ https://www.ncbi.nlm.nih.gov/pubmed/21873563 http://dx.doi.org/10.2337/dc11-1055 |
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