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Ultraviolet-A Light and Riboflavin Therapy for Acanthamoeba Keratitis: A Case Report

PURPOSE: To report ultraviolet-A (UV-A) light treatment in a patient with Acanthamoeba keratitis (AK). METHODS: Interventional case report. A standard protocol for ultraviolet corneal therapy, with a power emission of 3 mW/cm(2) and a wavelength of 370 nm, was used. The protocol included an 8-nm ban...

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Autores principales: Garduño-Vieyra, Leopoldo, Gonzalez-Sanchez, Claudia R., Hernandez-Da Mota, Sergio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177813/
https://www.ncbi.nlm.nih.gov/pubmed/21941509
http://dx.doi.org/10.1159/000331707
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author Garduño-Vieyra, Leopoldo
Gonzalez-Sanchez, Claudia R.
Hernandez-Da Mota, Sergio E.
author_facet Garduño-Vieyra, Leopoldo
Gonzalez-Sanchez, Claudia R.
Hernandez-Da Mota, Sergio E.
author_sort Garduño-Vieyra, Leopoldo
collection PubMed
description PURPOSE: To report ultraviolet-A (UV-A) light treatment in a patient with Acanthamoeba keratitis (AK). METHODS: Interventional case report. A standard protocol for ultraviolet corneal therapy, with a power emission of 3 mW/cm(2) and a wavelength of 370 nm, was used. The protocol included an 8-nm bandwidth at a 54-mm distance measured with a collimation system of diodes as well as a protective shield of riboflavin in a case of documented AK. RESULTS: A 54-year-old female patient with AK, showing no therapeutic response to a wide variety of topical antimicrobial agents and with a visual acuity of 20/400, was treated with UV-A therapy. The patient displayed a favourable response in the first 24 h after treatment, with improvement of symptoms, visual acuity (to 20/200) and biomicroscopy cornea with haze degree I. By the third week post-treatment, the patient was symptom-free. Her visual acuity was 20/30, and the affected cornea was clear. Five months after treatment, there had been no recurrence, and her vision was 20/20. CONCLUSIONS: Treatment with UV-A light was an effective therapy in this case of AK.
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spelling pubmed-31778132011-09-22 Ultraviolet-A Light and Riboflavin Therapy for Acanthamoeba Keratitis: A Case Report Garduño-Vieyra, Leopoldo Gonzalez-Sanchez, Claudia R. Hernandez-Da Mota, Sergio E. Case Rep Ophthalmol Published: August 2011 PURPOSE: To report ultraviolet-A (UV-A) light treatment in a patient with Acanthamoeba keratitis (AK). METHODS: Interventional case report. A standard protocol for ultraviolet corneal therapy, with a power emission of 3 mW/cm(2) and a wavelength of 370 nm, was used. The protocol included an 8-nm bandwidth at a 54-mm distance measured with a collimation system of diodes as well as a protective shield of riboflavin in a case of documented AK. RESULTS: A 54-year-old female patient with AK, showing no therapeutic response to a wide variety of topical antimicrobial agents and with a visual acuity of 20/400, was treated with UV-A therapy. The patient displayed a favourable response in the first 24 h after treatment, with improvement of symptoms, visual acuity (to 20/200) and biomicroscopy cornea with haze degree I. By the third week post-treatment, the patient was symptom-free. Her visual acuity was 20/30, and the affected cornea was clear. Five months after treatment, there had been no recurrence, and her vision was 20/20. CONCLUSIONS: Treatment with UV-A light was an effective therapy in this case of AK. S. Karger AG 2011-08-31 /pmc/articles/PMC3177813/ /pubmed/21941509 http://dx.doi.org/10.1159/000331707 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: August 2011
Garduño-Vieyra, Leopoldo
Gonzalez-Sanchez, Claudia R.
Hernandez-Da Mota, Sergio E.
Ultraviolet-A Light and Riboflavin Therapy for Acanthamoeba Keratitis: A Case Report
title Ultraviolet-A Light and Riboflavin Therapy for Acanthamoeba Keratitis: A Case Report
title_full Ultraviolet-A Light and Riboflavin Therapy for Acanthamoeba Keratitis: A Case Report
title_fullStr Ultraviolet-A Light and Riboflavin Therapy for Acanthamoeba Keratitis: A Case Report
title_full_unstemmed Ultraviolet-A Light and Riboflavin Therapy for Acanthamoeba Keratitis: A Case Report
title_short Ultraviolet-A Light and Riboflavin Therapy for Acanthamoeba Keratitis: A Case Report
title_sort ultraviolet-a light and riboflavin therapy for acanthamoeba keratitis: a case report
topic Published: August 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177813/
https://www.ncbi.nlm.nih.gov/pubmed/21941509
http://dx.doi.org/10.1159/000331707
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