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Functional Heterogeneity of Breast Fibroblasts Is Defined by a Prostaglandin Secretory Phenotype that Promotes Expansion of Cancer-Stem Like Cells

Fibroblasts are important in orchestrating various functions necessary for maintaining normal tissue homeostasis as well as promoting malignant tumor growth. Significant evidence indicates that fibroblasts are functionally heterogeneous with respect to their ability to promote tumor growth, but mark...

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Detalles Bibliográficos
Autores principales: Rudnick, Jenny A., Arendt, Lisa M., Klebba, Ina, Hinds, John W., Iyer, Vandana, Gupta, Piyush B., Naber, Stephen P., Kuperwasser, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177828/
https://www.ncbi.nlm.nih.gov/pubmed/21957456
http://dx.doi.org/10.1371/journal.pone.0024605