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Is There a Classical Nonsense-Mediated Decay Pathway in Trypanosomes?
In many eukaryotes, messenger RNAs with premature termination codons are destroyed by a process called “nonsense-mediated decay”, which requires the RNA helicase Upf1 and also, usually, an interacting factor, Upf2. Recognition of premature termination codons may rely on their distance from either a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177853/ https://www.ncbi.nlm.nih.gov/pubmed/21957477 http://dx.doi.org/10.1371/journal.pone.0025112 |