Cargando…

The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents

The emergence of multidrug-resistant cancers and the lack of targeted therapies for many cancers underscore an unmet need for new therapeutics with novel modes of action towards cancer cells. Host-defense peptides often exhibit selective cytotoxicity towards cancer cells and show potential as anti-c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morash, Michael G., Douglas, Susan E., Robotham, Anna, Ridley, Christina M., Gallant, Jeffrey W., Soanes, Kelly H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Limited 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177944/ https://www.ncbi.nlm.nih.gov/pubmed/21729875 http://dx.doi.org/10.1242/dmm.007310

Ejemplares similares

Pleurocidin peptides: a new class of anti-cancer agents?
Publicado: (2011)

Assessing the Morphological and Behavioral Toxicity of Catechol Using Larval Zebrafish
por: Morash, Michael G., et al.
Publicado: (2022)

Pleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts
por: Hilchie, Ashley L, et al.
Publicado: (2011)

Investigating Potential Applications of the Fish Anti-Microbial Peptide Pleurocidin: A Systematic Review
por: McMillan, Katelyn A. M., et al.
Publicado: (2021)

Molecular modelling and docking analysis of pleurocidin (an antimicrobial peptide) like peptides with enterotoxin H from Klebsilla pneumonia
por: Bupesh, Giridharan, et al.
Publicado: (2019)

Use of the Zebrafish Larvae as a Model to Study Cigarette Smoke Condensate Toxicity
por: Ellis, Lee D., et al.
Publicado: (2014)

Recombinant Expression of Pleurocidin cDNA Using the Pichia pastoris Expression System
por: Burrowes, Olive-Jean, et al.
Publicado: (2005)

Antibacterial and Anticancer Activities of Pleurocidin-Amide, a Potent Marine Antimicrobial Peptide Derived from Winter Flounder, Pleuronectes americanus
por: Hsu, Hui-Chen, et al.
Publicado: (2022)

Truncated Pleurocidin Derivative with High Pepsin Hydrolysis Resistance to Combat Multidrug-Resistant Pathogens
por: Wang, Dejuan, et al.
Publicado: (2022)

MDA-MB-231 Breast Cancer Cells Resistant to Pleurocidin-Family Lytic Peptides Are Chemosensitive and Exhibit Reduced Tumor-Forming Capacity
por: Hilchie, Ashley L., et al.
Publicado: (2020)

A Pleurocidin-Like Peptide from Poecilia Mexicana Fish Induces Selective Cytotoxicity in Leukemia Jurkat Cells Through The Apoptosis Pathway
por: Ebrahimdoost, Mostafa, et al.
Publicado: (2023)

A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy
por: Manzo, Giorgia, et al.
Publicado: (2020)

Perturbation of Defense Pathways by Low-Dose Arsenic Exposure in Zebrafish Embryos
por: Mattingly, Carolyn J., et al.
Publicado: (2009)

Pleurocidin Peptide Enhances Grouper Anti-Vibrio harveyi Immunity Elicited by Poly(lactide-co-glycolide)-Encapsulated Recombinant Glyceraldehyde-3-phosphate Dehydrogenase
por: Chuang, Shu-Chun, et al.
Publicado: (2014)

Oncolytic Activities of Host Defense Peptides
por: Al-Benna, Sammy, et al.
Publicado: (2011)

Reassessing the Host Defense Peptide Landscape
por: Haney, Evan F., et al.
Publicado: (2019)

The future of recombinant host defense peptides
por: Roca-Pinilla, Ramon, et al.
Publicado: (2022)

Functions of Cationic Host Defense Peptides in Immunity
por: Hemshekhar, Mahadevappa, et al.
Publicado: (2016)

Antimicrobial peptides of buffalo and their role in host defenses
por: Chanu, Khangembam Victoria, et al.
Publicado: (2018)

Host defense peptides: An insight into the antimicrobial world
por: Gupta, Shiva, et al.
Publicado: (2018)

Toward the Discovery of Host-Defense Peptides in Plants
por: Petre, Benjamin
Publicado: (2020)

Regulation of Host Defense Peptide Synthesis by Polyphenols
por: Tobin, Isabel, et al.
Publicado: (2023)

Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success
por: Etayash, Hashem, et al.
Publicado: (2021)

Protective Immunity against Vibrio harveyi in Grouper Induced by Single Vaccination with Poly (Lactide-co-glycolide) Microparticles Releasing Pleurocidin Peptide and Recombinant Glyceraldehyde-3-phosphate Dehydrogenase
por: Liu, Shang-Pin, et al.
Publicado: (2020)

Epithelial antimicrobial peptides in host defense against infection
por: Bals, Robert
Publicado: (2000)

Regulation of the Intestinal Barrier Function by Host Defense Peptides
por: Robinson, Kelsy, et al.
Publicado: (2015)

Designed Host Defense Peptides for the Treatment of Bacterial Keratitis
por: Clemens, L. Edward, et al.
Publicado: (2017)

Expression and Function of Host Defense Peptides at Inflammation Sites
por: Prasad, Suhanya V., et al.
Publicado: (2019)

Strategies in Translating the Therapeutic Potentials of Host Defense Peptides
por: Ting, Darren Shu Jeng, et al.
Publicado: (2020)

Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action
por: Drayton, Matthew, et al.
Publicado: (2021)

Host Defense Peptides as Templates for Antifungal Drug Development
por: Basso, Virginia, et al.
Publicado: (2020)

The Network of Colonic Host Defense Peptides as an Innate Immune Defense Against Enteropathogenic Bacteria
por: Blyth, Graham A. D., et al.
Publicado: (2020)

Protein‐Functionalized DNA Nanostructures as Tools to Control Transcription in Zebrafish Embryos
por: Angelin, Alessandro, et al.
Publicado: (2016)

Enteric defensins: antibiotic peptide components of intestinal host defense
Publicado: (1992)

Proteolysis of Human Thrombin Generates Novel Host Defense Peptides
por: Papareddy, Praveen, et al.
Publicado: (2010)

Multiple Immune-Modulatory Functions Of Cathelicidin Host Defense Peptides
por: Choi, Ka-Yee (Grace), et al.
Publicado: (2012)

Anti-antimicrobial Peptides: FOLDING-MEDIATED HOST DEFENSE ANTAGONISTS
por: Ryan, Lloyd, et al.
Publicado: (2013)

Current and Potential Applications of Host-Defense Peptides and Proteins in Urology
por: Lo, Joey Chor Yee, et al.
Publicado: (2015)

Roles of d-Amino Acids on the Bioactivity of Host Defense Peptides
por: Li, Hao, et al.
Publicado: (2016)

Tissue expression and antibacterial activity of host defense peptides in chicken
por: Lee, Mi Ok, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2b8i2uteo3oqt2jjmmt4a7j05b