Mice with null mutation of Ceacam1 develop nonalcoholic steatohepatitis

Transgenic liver-specific inactivation of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM1) impairs hepatic insulin clearance and causes hyperinsulinemia, insulin resistance, elevation in hepatic and serum triglyceride levels, and visceral obesity. It also predisposes to nonalcho...

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Detalles Bibliográficos
Autores principales: Ghosh, Sumona, Kaw, Meenakshi, Patel, Payal R, Ledford, Kelly J, Bowman, Thomas A, McInerney, Marcia F, Erickson, Sandra K, Bourey, Raymond E, Najjar, Sonia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177946/
https://www.ncbi.nlm.nih.gov/pubmed/21949477

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