GLUT2 Accumulation in Enterocyte Apical and Intracellular Membranes: A Study in Morbidly Obese Human Subjects and ob/ob and High Fat–Fed Mice

OBJECTIVE: In healthy rodents, intestinal sugar absorption in response to sugar-rich meals and insulin is regulated by GLUT2 in enterocyte plasma membranes. Loss of insulin action maintains apical GLUT2 location. In human enterocytes, apical GLUT2 location has not been reported but may be revealed u...

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Detalles Bibliográficos
Autores principales: Ait-Omar, Amal, Monteiro-Sepulveda, Milena, Poitou, Christine, Le Gall, Maude, Cotillard, Aurélie, Gilet, Jules, Garbin, Kevin, Houllier, Anne, Château, Danièle, Lacombe, Amélie, Veyrie, Nicolas, Hugol, Danielle, Tordjman, Joan, Magnan, Christophe, Serradas, Patricia, Clément, Karine, Leturque, Armelle, Brot-Laroche, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178286/
https://www.ncbi.nlm.nih.gov/pubmed/21852673
http://dx.doi.org/10.2337/db10-1740

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