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Inhibition of Id1 Augments Insulin Secretion and Protects Against High-Fat Diet–Induced Glucose Intolerance

OBJECTIVE: The molecular mechanisms responsible for pancreatic β-cell dysfunction in type 2 diabetes remain unresolved. Increased expression of the helix-loop-helix protein Id1 has been found in islets of diabetic mice and in vitro models of β-cell dysfunction. Here, we investigated the role of Id1...

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Detalles Bibliográficos
Autores principales:	Åkerfeldt, Mia C., Laybutt, D. Ross
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178288/ https://www.ncbi.nlm.nih.gov/pubmed/21940780 http://dx.doi.org/10.2337/db11-0083

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