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Anti-inflammatory and Antioxidant Properties of HDLs Are Impaired in Type 2 Diabetes

OBJECTIVE: In mice, 4F, an apolipoprotein A-I mimetic peptide that restores HDL function, prevents diabetes-induced atherosclerosis. We sought to determine whether HDL function is impaired in type 2 diabetic (T2D) patients and whether 4F treatment improves HDL function in T2D patient plasma in vitro...

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Detalles Bibliográficos
Autores principales:	Morgantini, Cecilia, Natali, Andrea, Boldrini, Beatrice, Imaizumi, Satoshi, Navab, Mohamad, Fogelman, Alan M., Ferrannini, Ele, Reddy, Srinivasa T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Pharmacology and Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178289/ https://www.ncbi.nlm.nih.gov/pubmed/21852676 http://dx.doi.org/10.2337/db11-0378

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