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Advanced Glycation End Products Are Direct Modulators of β-Cell Function

OBJECTIVE: Excess accumulation of advanced glycation end products (AGEs) contributes to aging and chronic diseases. We aimed to obtain evidence that exposure to AGEs plays a role in the development of type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS: The effect of AGEs was examined on insulin secr...

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Detalles Bibliográficos
Autores principales:	Coughlan, Melinda T., Yap, Felicia Y.T., Tong, David C.K., Andrikopoulos, Sofianos, Gasser, Anna, Thallas-Bonke, Vicki, Webster, Diane E., Miyazaki, Jun-ichi, Kay, Thomas W., Slattery, Robyn M., Kaye, David M., Drew, Brian G., Kingwell, Bronwyn A., Fourlanos, Spiros, Groop, Per-Henrik, Harrison, Leonard C., Knip, Mikael, Forbes, Josephine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178291/ https://www.ncbi.nlm.nih.gov/pubmed/21911745 http://dx.doi.org/10.2337/db10-1033

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